ObjectiveThe COVID-19 pandemic and government measures implemented to counter the spread of the infection may be a major stressor affecting the psychological health of university students. This study aimed to explore how anxiety symptoms changed during the pandemic.Methods676 students at Zurich University of Applied Sciences participated in the first and second survey waves. Anxiety symptoms were assessed using the Generalized Anxiety Disorder-Scale-7. Risk and protective factors were examined.ResultsGAD-7 scores decreased significantly from T0 to T1. Participants with moderate-to-severe anxiety score were (...) 20.2 and 15.6% at T0 and T1, respectively. The following positively predicted anxiety: older age, female gender, non-Swiss nationality, loneliness, participants’ concern about their own health, and interaction between time and participants’ concern about their own health. Resilience and social support negatively predicted anxiety.ConclusionsOur findings provide information for public health measures and psychological interventions supporting the mental health of university students during the COVID-19 emergency. (shrink)